You can't get a formatted treeview of raw JSON post data in chrome inspector, only the response can be inspected in this way. Makes debugging broken uploads difficult at times. That's pretty much the only feature of firebug I miss.

The only chrome inspector feature I know of that firebug doesn't have a real equivalent for is the heap snapshot and compare tool. Really handy to track down memory leaks.

Other than that it's indeed down to personal preference.