In the last year or so of his life, Stephen Hawking's long-EOL'ed speech synthesizer was showing signs of failing, and the replacement was an emulator based in part on low-level DSP emulation code from bsnes/Higan, as the "Nintendo DSP-1" used as a math coprocessor on some SNES games was coincidentally the same processor family [1] [2]. Games using this processor had been supported by other emulators for a long time, but they did so with a high-level implementation of the Nintendo firmware calls.

[1] https://www.sfchronicle.com/bayarea/article/The-Silicon-Vall...

[2] https://en.wikipedia.org/wiki/List_of_Super_NES_enhancement_...